전문대학원 소개
한양대학교 의생명공학전문대학원
한양대학교 의생명공학전문대학원
국문 (한자) 성명 | 전공분야 / 연구분야 | Stem cell biology, Dvelopmental biotechnology | |
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영문성명 | KYE-SEONG KIM | URL | |
현직급 | 교수 | 연구실 전화번호 | 02 - 2220 - 0607 |
소속 | 의생명공학전문대학원 Graduate School of Biomedical Science and Engineering | 학교 이메일 주소 | ks66kim@hanyang.ac.kr |
학사학위 취득 관련 사항 | 수의학사, 서울대학교 (1988), B.S. in Veterinary Medicine, Seoul National University (1988) |
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석사학위 취득 관련 사항 | 수의학석사, 서울대학교 (1990), M.S. in Veterinary Medicine, Seoul National University (1990) |
박사학위 취득 관련 사항 | 수의학박사, 서울대학교 (1996), Ph.D. in Veterinary Theriogenology, Seoul National University (1996) |
주요경력 | 박사연구원, 미국 펜실베이니아대학교 (1996-2000), Research associate, University of Pennsylvania (1996-2000) 조교수, 차의과대학교 (2000-2004), Assistant professor, CHA University (2000-2004) |
실험실 명 (국문) | 줄기세포생물학연구실 |
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실험실 명 (영문) | Laboratory of Stem Cell Biology |
Research interest | The role of stem cells in development and disease Creating disease model with pluripotent stem cells |
대표 논문 | 1. Human embryonic stem cells express a unique set of microRNAs. Developmental Biology 2004. 2. Checkpoint-apoptosis uncoupling in human and mouse embryonic stem cells: a source of karyotypic instability. Blood 2007. |
연구 분야 대표 그림 |
1. Genome-scale screening of deubiquitinase subfamily identifies USP3 as a stabilizer of Cdc25A regulating cell cycle in cancer. Cell Death and Differentiation 2020.
2. USP32 confers cancer cell resistance to YM155 via promoting ER-associated degradation of solute carrier protein SLC35F2. Theranostics 2021.
3. Genome-wide screening for deubiquitinase subfamily identifies ubiquitin-specific protease 49 as a novel regulator of odontogenesis. Cell Death & Differentiation 2022.
4. Dual role of deubiquitinating enzyme USP19 regulates mitotic progression and tumorigenesis by stabilizing surviving. Molecular Therapy 2022.
5. CRISPR/Cas9-based genome-wide screening for deubiquitinase subfamily identifies USP1 regulating MAST1-driven cisplatin-resistance in cancer cells. Theranostics 2022.
6. CRISPR/Cas9-based genome-wide screening of the deubiquitinase subfamily identifies USP3 as a protein stabilizer of REST blocking neuronal differentiation and promotes neuroblastoma tumorigenesis. Journal of Experimental & Clinical Cancer Research 2023.